Fig. 6. Effects of inhibitors of H₂S synthesis on hypoxic (N₂) relaxation of pre-contracted bladders. The cystathionine -lyase inhibitor, D,L-propargylglycine (PPG; 20 mmol l^-1) significantly decreased a N₂ relaxation of 10 µmol l^-1 carbachol-pre-contracted bladders and a mixture of PPG and the cystathionine ß-synthase inhibitor, amino-oxyacetic acid (AOA; 1 mmol l^-1) significantly inhibited N₂ relaxation of both 80 mmol l^-1 KCl- and 80 mmol l^-1 KAc-pre-contracted bladders (N=4 for all experimental groups; N=8 for controls). Values are means ± s.e.m. ^*Significantly different from the respective control; significantly different from all other conditions.