Fig. 4. Profile of agNAT8-mediated amino acid-induced currents. The upper line combines typical currents of agNAT8-expressing oocytes upon a trial application of selected substrates at 2 mmol l^-1 concentrations. The lower histogram incorporates mean values of induced responses upon application of 1 mmol l^-1 concentration of selected substrates normalized to Phe induced currents (values are mean + s.d.; N 3 recordings for at least three different oocytes for each data point). Holding potentials for all recordings were -50 mV. Standard abbreviations of amino acids and neurotransmitters are used. Arrows highlight the D-isomer of phenylalanine.