Fig. 1. The pattern of tissue-specific transcript responses to chronic cooling. The numbers on the vertical axis represent the 23 clusters determined by K-means technique of the 1701 genes not involved in the tissue common response. The average expression for all genes at a particular time point for each tissue in the cooling treatment was calculated relative to control specimens held throughout at 30°C. Red indicates upregulation and green, downregulation. Redrawn and simplified from a figure published elsewhere (Gracey et al., 2004).