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Figure 4


Fig. 4. Strain-selective enhancement of long-term potentiation (LTP) by temporally compressed stimulation. (A) There was no significant difference in LTP between B6 (N=7 mice, 7 slices) and 129/SvEms (N=5 mice, 5 slices) hippocampi when the interburst interval was reduced to 3 s. (B,C) LTP in DBA (N=6 mice, 6 slices) and CBA (N=7 mice, 7 slices) strains remained deficient relative to that of the B6 strain. The B6 curve in A is repeated in B and C for comparison with other strains. Sample sweeps were recorded at t=130 min (110 min post-induction). Taken from (Nguyen et al., 2000b). (Copyright 2000, The American Physiological Society, used with permission.)