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Figure 6


Fig. 6. Changes in the cytosolic Ca2+ mobilisation of pancreatic acinar cells in response to perfusion with FCCP (0.5 µmol l-1), followed by tBHP (1 mmol l-1) in the presence of (A) 2-aminoethoxydiphenylborane (2-APB, 30 µmol l-1) or (B) ryanodine (50 µmol l-1). All experiments were performed in a Ca2+-free solution (1 mmol l-1 EGTA was added). Traces are representative of 37 and 46 cells taken from 2 and 3 different experiments, respectively. (C) Histogram of the mean post-stimulus [Ca2+]c under different experimental conditions of 2-3 independent experiments. Values are means ± s.e.m. *P<0.05.