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Figure 4


Fig. 4. Effect of depletion of Ca2+ mitochondrial pools on tBHP-evoked Ca2+ release in pancreatic acinar cells. (A) Cells were perfused with 0.5 µmol l-1 FCCP, followed by perfusion with 1 mmol l-1 tBHP, in Ca2+-free medium. (B) Cells were perfused with 1 mmol l-1 tBHP, followed by perfusion with 0.5 µmol l-1 FCCP, in Ca2+-free medium. Traces are representative of 27 and 18 such cells taken from 7 and 6 different experiments, respectively.