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Figure 2


Fig. 2. Effects of stimulation with 5-HT on (A) transepithelial potential (TEP), (B) basolateral membrane potential (Vbl), (C), lumen pH and(D) intracellular pH. The numbered phases of the response of transepithelial potential to 5-HT are described in the text. Open arrows indicate addition of 5-HT. Downward-pointing solid arrows indicate impalement of the cell or lumen and upward-pointing solid arrows indicate the removal of the electrode from the cell or lumen. (E,F) Values are means + s.e.m.; N=5 tubules) for lumen and intracellular pH, respectively. The asterisk indicates a significant difference (P<0.05, Student's t-test) relative to unstimulated (i.e. phase 0) tubules.