Fig. 1. Time course of changes in temperature, hematocrit and ventricular mass. Temperatures were monitored for 5 weeks prior to phenylhydrazine treatment at week 0 (dotted lines). Open circles represent values for anemic animals and solid circles for untreated animals, with error bars = 1 S.E.M. The analyses from 2–25 weeks compared treated animals with time-matched controls. The data collected at 1, 2, 4, and 8 days were compared with pre-treatment values. ^*Significantly different from control animals. RBC, red blood cells.