JEB -- Leader and O'Donnell 208 (23): 4363 Figure IG10

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Fig. 10. Effects of the MRP2 inhibitors MK-571 and probenecid (PROB) on transepithelial flux of Texas Red across isolated Drosophila tubules set up in Ramsay assays. Each bar shows the flux (mean + S.E.M.) for 7–9 tubules (MK-571) or 10 tubules (probenecid) bathed in saline containing the indicated concentration (µmol l^–1) of Texas Red in the absence (filled bars) or presence (open bars) of the indicated inhibitor. Asterisks indicate significant (P<0.05) decreases in flux in the presence of each drug, relative to the corresponding controls.