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Fig. 6. Inhibition of secretion by a range of sulphonylureas. (A) Diazoxide, (B) minoxidil, (C) tolbutamide or (D) glibenclamide were added after 30 min. Drosophila corticotropin releasing factor-like peptide (dCRF) and Drosophila leucokinin (dLK) were added (to final concentrations of 10-7 mol l-1) after a further 30 min to stimulate the secretion rate. Secretion rates are shown as means ± S.E.M. (N=7).