Fig. 11. Transport and metabolism of ¹²⁵I-labelled glibenclamide. (A) Transport rates and (B) secreted:bathing ratios of [¹²⁵I]glibenclamide at different bathing glibenclamide concentrations. (C) Thin-layer chromatography plate image. Lane 1, authentic [¹²⁵I]glibenclamide; lane 2, secreted drop after [¹²⁵I]glibenclamide was added to the bathing solution; lane 3, secreted drop where no radiolabelled glibenclamide was added. Lower and upper bars represent the origin and solvent front, respectively.