Fig. 1. Potassium currents (I_K) and sodium currents (I_Na) generated in a voltage-clamp simulation. (A) The simulated potassium currents are those obtained during 100 ms depolarizations from a holding potential of –90 mV to a range of potentials from –70 to +60 mV in 10 mV steps. (B) The simulated sodium currents were those obtained in response to a 1 ms depolarization to a range of potentials from –70 to + 70 mV in 10 mV steps.