Fig. 7. The serial effects of -CTx AuIB and -CTx MII are also additive, suggesting that 3ß2- and 3ß4-nAChRs can exist as independent entities in submucosal neurones. (A) High-resolution image of a submucosal ganglion (inverted grey scale), showing the individual neurones identified by numbers. The position of the stimulation electrode is shown schematically. (B) Pixel map of the NeuroCCD-SM camera depicting, in red, the area of interest. (C) Experimental protocol. (D) Spatially averaged optical outputs from the red pixels in B (represented by bars whose heights indicate the amplitude of the voltage change under each experimental condition in the row labelled `Ganglion') and from selected individual neurones (`Cells'). Magnification, 100x. `Ganglion' signals were high-pass filtered at 6.6 Hz. `Cell' traces were low-pass filtered at 200 Hz.