Fig. 10. nAChR antagonists can also enhance synaptically evoked responses in the myenteric plexus. (A) High-resolution image of a myenteric ganglion (inverted grey scale), showing three individual neurones identified by numbers. (B) Pixel map of the NeuroCCD-SM camera depicting, in dark grey, the area of interest. Notice that, as in Fig. 8, the highlighted area is considerably bigger than the ganglion itself. (C) Low-magnification image of the preparation (20x), illustrating the location of the stimulating electrode (E_s) with respect to the recording area. (D) Experimental protocol. (E) Spatially averaged optical outputs from the dark-grey pixels in B (represented by bars whose heights indicate the amplitude of the voltage change under each experimental condition in the row labelled `Ganglion') and from the pixels that outline neurones 1, 2 and 3 (`Cells'). Magnification, 100x. `Ganglion' signals were high-pass filtered at 6.6 Hz. `Cell' traces were unfiltered.