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Fig. 1. (A) Plasma glucose concentrations (mmol l–1). (B) Urine glucose concentrations (mmol l–1). Values are means ± 1 S.E.M. (N=7). * indicates a significant difference (P<0.05) between the indicated value and the previous 12 h value; a indicates a significant difference (P<0.05) between the indicated value and the glucose-only infusion value at the same time point.