Fig. 4. The EGL-19 L-type calcium channel conducts the HVA current in the pharynx.
(A) Total currents in cca-1 and cca-1; egl-19. 100 ms
depolarizing pulses were applied in 10 mV increments from the holding
potential of -80 mV (same protocol as in
Fig. 2A). (B) HVA currents in
wild type and egl-19. The LVA current was inactivated with a 300 ms
prepulse to -40 mV (same protocol as in
Fig. 2B). (C) Current-voltage
dependencies of HVA currents in WT and egl-19 (peak amplitudes;
prepulse protocol). (D) Activation time constants of HVA currents in WT and
egl-19; *significantly different by t-test,
P<0.01.