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Fig. 6. Current traces showing that the reduction of glutamate-induced current under continuous flow conditions is established rapidly. The glutamate-induced current was produced repeatedly by 25 s applications of solutions containing various concentrations of glutamate (numbers in the figure, µmol l-1) to oocytes expressing NMDAR only (EAAT3- oocytes in panel A) or co-expression oocytes (EAAT3+ oocytes in panel B).