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Fig. 8. Effect of isoproterenol (ISO) in the presence of low extracellular [Ca2+]. (A) Representative ICa recordings in control (CON) and with 1 µmol l–1 ISO + low extracellular [Ca2+] (ISO + low Ca2+). (B) Corresponding recordings of Caf releasable SR Ca2+ load after a 10 s depolarization to –30, –10 or +10 mV.