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Fig. 5. Effect of internal organic anions on 0.1 mmol l–1 [14C]oxalate uptake into hepatopancreatic BBMV. Vesicles were loaded with 100 mmol l–1 TMA-gluconate, 100 mmol l–1 K-gluconate and 5 mmol l–1 of the indicated anion (substituted iso-osmotically for TMA). Incubation media contained 100 mmol l–1 TMA-gluconate, 100 mmol l–1 K-gluconate and 0.1 mmol l–1 [14C]oxalate. All media contained 40 mmol l–1 Hepes-Tris and 50 µmol l–1 valinomycin at pH 7.0. Control anion, gluconate.