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Fig. 6. Cardiovascular responses to adenosine (Ado) injections (at time zero) on (A) heart rate (fH), (B) ventral aortic blood pressure (PVA) and (C) dorsal aortic blood pressure (PDA) in control (•, N=7) and aminophylline-treated ({circ}, N=6) sharks. All values are mean ± S.E.M. Time-dependent changes were tested using repeated measures ANOVA with Dunnet post-test. Lines indicate the time periods that differ significantly from the last normoxic value (P<0.05). A significant ANOVA between aminophylline-treated and control sharks in response to adenosine injections is indicated by an asterisk.