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Fig. 5. A twofold increase in intra-abdominal pressure (PIA) caused a decrease in post caval vein transmural pressure (PTRANS) and a 52% decrease in flow through the post cava vein (PC). Despite inter-animal variation, a threefold increase in PIA significantly decreased PTRANS but did not alter PC. The gray panel indicates negative PTRANS which theoretically correspond to the partial or complete collapse of the post cava vein. The open square represents resting PIA, the black square represents double PIA and the gray square represents triple PIA. The dotted line indicates resting PC. *Indicates a significant decrease in PTRANS and {dagger}indicates a significant decrease in PC (Bonferroni's corrected paired t-tests, P<0.05). Data presented are means ± S.E.M. (N=5).