Fig. 4. CAPA transcript expression in the brain of Manduca sexta. Dorsal (A) and ventral (B) 3rd-instar brain. (C) Anterior view of a different 3rd-instar brain showing the 10 pairs of CAPA-expressing cells. Arrowheads, cluster of five cells near dorsal midline; concave arrowhead, single dorsal cell in the middle of each brain hemisphere; convex arrowhead, single dorsal cell located antero-laterally in each hemisphere; convex arrow, single dorsolateral cell; arrows, cluster of three ventral cells. (D, top) Anterior view of a pharate adult brain showing the CAPA-expressing cell (arrowheads); (D, bottom) anterior view of the pharate adult subesophageal ganglion fused to the brain, showing a pair of CAPA-expressing cells (concave arrowheads). Scale bar, 100 µm.