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Fig. 4. Seasonal changes in the ß-adrenergically stimulated RBC Na+/H+ exchanger (ßNHE) activity (filled circles) and ßNHE mRNA levels (relative to August value; open circles). Note one outlying ßNHE mRNA value is plotted separately. Values are means ± S.E.M. (N=8 for ßNHE activity values and N=3-8 for ßNHE mRNA values). The inset shows the linear regression curve for ßNHE activity vs ßNHE mRNA values (P=0.038, f(x)=135.0x/(0.274+x), r2=0.538).