(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 10. The effect of the D1-selective antagonists SKF83566 and flupenthixol on dopamine-stimulated glycoprotein secretion by the albumen glands of H. duryi. The application of dopamine (50 µmol l-1) stimulated glycoprotein secretion more than fourfold compared with control glands in saline. (A) In the presence of SKF83566 (50 µmol l-1), dopamine-stimulated glycoprotein secretion was significantly suppressed. Abbreviations: CON, control; DA, dopamine; DA+SKF, dopamine + SKF83566. Bars represent the mean ± S.E.M. of 15–20 samples (*P<0.05, Tukey test). (B) The D1-selective antagonist flupenthixol also caused a significant inhibition of dopamine-stimulated protein secretion in isolated albumen glands. Abbreviations: CON, control; DA, dopamine; DA+FLU, dopamine + flupenthixol. Neither antagonist had an effect on basal glycoprotein secretion. Bars represent the mean ± S.E.M. of 15–20 samples (*P<0.05, Tukey test).