Fig. 7. Effect of diflouromethylornithine (DFMO) on contractile force in
steroid-treated ventricle strips from both male (A) and female (B) rainbow
trout. Strips were treated with DFMO (10 mmol l1) for 10 min
prior to exposure to 11-ketotestosterone (11KT; 0.3 µmol
l1), testosterone (T; 0.3 µmol l1),
cortisol (C; 0.1 µmol l1 in males and 0.01 µmol
l1 in females) or estradiol (E2; 1.0 nmol
l1). DFMO had no independent effect on contractile force;
however, DFMO did block the inotropic effects of androgens, C and E2. All
values are means + S.E.M.
(N=69). *P<0.05 versus EtOH control
strips.