Fig. 3. Maximum likelihood phenogram (mid-point rooted) based on a DNA alignment of the coding sequence of arginase genes in vertebrates and three nonvertebrate eukaryotes. Nomenclature of genes is identical to that used in Fig. 2, with the inclusion of three nonvertebrate eukaryote arginase sequences: Neurospora crassa (Necr), Schizosaccharomyces pombe (Scpo) and Schistosoma japonicum (Scja). The location of the common ancestor of all vertebrate cytosolic arginase genes is shown by the arrow. Bootstrap values, based on 300 bootstraps replicates, are placed to the left of the appropriate nodes.