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Fig. 8. Time courses of EOD duration and amplitude responses for 5-HT doses of 0.75 nmol g-1 and higher. Points plotted are pre-injection baseline, 50% of peak, peak response, and response half-life. (A) Dur-P1 (duration of the first EOD phase) showed no clear response to 5-HT. (B) {tau}-P2, (repolarization time of the second phase) showed the clearest response, with a bimodal distribution of peaks occurring at approx. 25 and 90 min after injection. (C) Amplitude was variable; if it rose, it peaked by approx. 30 min.