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Fig. 7. Amplitude of the novelty response as a function of the change in sLEOD parameters. In these experiments, the object load was changed from open circuit to a given resistor value (red symbols) or a given capacitor value (blue symbols). (A) Amplitude of novelty response (interval shortening as a percentage of the basal interval) as a function of energy (as the change in rms value) of the sLEOD. Linear regression analysis was performed for experiments in which the change in sLEOD was obtained by loading the object with resistors: amplitude of the novelty response = 0.15xlog({Delta}rms/0.35); r2=0.81, N=15, P<0.0001; the regression line is drawn in red. Changes from open circuit to capacitive loads evoked larger responses than changes from open circuit to resistive loads, which generated sLEODs with the same rms value, except at the extremes of the range. (B) Difference between the predicted amplitude of the novelty response minus the measured data as a function of the {Delta}sV1/sV3 ratio. The correlation was statistically significant only for experiments performed with capacitors (r2=0.75, N=30, P<0.001). (C) Difference between the predicted amplitude of the novelty response minus the measured data as a function of the {Delta}sV4/sV3 ratio. The correlation was statistically significant only for experiments performed with capacitors (r2=0.75, N=30, P<0.001).