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Fig. 8. Changes in mean (±S.E.M.) heart rate (fH) following medullary injections of glutamate (40-100 nl) in five animals. A marked bradycardia was blocked by prior application of MK-801 in the same sites. * indicates significant changes from pre-injection values at P<0.01, and # indicates a significant difference in the same time point before and after injection of MK-801 at P<0.01.