Fig. 5. Effects of hypoxia (FI_O2=fraction of oxygen in the inspired air) on the distribution of blood flows and cardiac parameters on two consecutive days exposure to hypoxia (filled and unfilled circles, respectively). (A) Systemic blood flow (_sys); (B) net shunt fraction (_pc/_sys); (C) pulmocutaneous blood flow (_pc); (D) net shunt flow (_shunt); (E) heart rate (fH) and (F) stroke volume (VS). The dotted lines represent the condition where there is no net shunt. Significant effects of hypoxia during either the first or second exposure are marked with an asterisk. Significant effects between first and second exposure are marked with a dagger. Data are presented as means ± 1 S.E.M. (N=6).