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Fig. 5. Dose-response curves showing the relationship between cardioexcitatory substances — (A) acetylcholine (ACh), (B) serotonin (5-HT), (C) octopamine (OA), (D) glutamate (Glu) and (E) proctolin (Proc) — and amplitude of pressure pulses of the fifth lateral artery (LA5; filled circle), heart rate (open square) and contraction force of the heart (open triangle). All data (mean ± S.D., N=3) were obtained from one preparation for three times applications per one dose. Each of the five graphs was obtained from a different specimen. The values plotted for pressure pulses, heart rate and contraction force were obtained at the maximum change of the amplitude of pressure pulses.