(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 2. Sequence analysis of trout Na+/K+-ATPase {alpha}-isoforms. (A) N-terminal isoform-specific identity sequence (ns), (B) central isoform-specific identity sequence (cs), (C) predicted structure of the Na+/K+-ATPase {alpha}-subunit protein showing (f) transmembrane domains, (g) ATP binding site, and (h) a highly conserved area found in all P-type ATPases. Asterisks indicate conserved aas among all isoforms; colons indicate the presence of a conservative aa substitution; stops indicate a semi-conservative aa substitution. (D,E) Percentage variability among isoforms was determined by sliding window analysis on the predicted aa sequence (D) and cDNA sequence (E). Sliding window analysis used overlapping windows of 50 to assess variability.