Fig. 5. Effect of hyperoxia on the distance from the lens surface to the border of the organelle-free zone (OFZ). (A) At all ages examined, the distance from the equatorial surface of the lens to the border of the OFZ (d1 and d2; see Fig. 3B) was significantly greater in hyperoxic lenses (open circles) compared with normoxic controls (closed circles). (B) Hyperoxia caused an increase in the distance from the anterior pole to the OFZ border (d3). (C) The distance from the posterior pole of the lens to the border of the OFZ (d4) was significantly greater in hyperoxic lenses.