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Fig. 7. (A,B) Superfusion with nicotine (100 µmol l-1, 600 s; horizontal bars) promotes bursting activity in SWA Dahlgren cells. (A) Nicotine induces a transition from tonic to bursting activity in a Dahlgren cell recorded intracellularly. (B) Extracellular recording shows no change in ongoing bursting activity in at least three Dahlgren cells in response to nicotine. (C) Superfusion with nicotine (100 µmol l-1, 600 s; horizontal bar) inhibits Dahlgren cells in FWA CNSS. Three bursting units extracted from an extracellular recording become silent following application of nicotine; only one resumes firing after 15 min washout.