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Fig. 4. Correlated changes in rates of oxygen consumption and intracellular (A) and extracellular (B) bicarbonate concentrations determined in hepatocytes isolated from P. brachycephalum. Intracellular values were measured after 50 min of exposure to normocapnic and hypercapnic media of different pH. *Oxygen consumption rate significantly different from the respective control value at pHe 7.90. Values are means ± S.D., N=4.