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Fig. 9. KAAT1 wild type (WT) uptake at pH 7.5 and pH 10. Upper panel: bars A and B, 0.2 mmoll-1 [3H]-L-leucine at pH 7.5 and pH 10, respectively; C and D, 0.2 mmoll-1 [3H]-L-lysine uptake at pH 7.5 and pH 10, respectively; E, 0.2 mmoll-1 [3H]-L-leucine uptake with 10 mmoll-1 lysine; F, 0.2 mmoll-1 [3H]-L-lysine with 10.0 mmoll-1 leucine; G and H, 10 mmoll-1 [3H]-L-leucine and 10 mmoll-1 [3H]-L-lysine uptake, respectively, by water-injected oocytes. Lower panel: currents measured in KAAT1 cRNA-injected oocytes in Na+-free K+ medium with lysine added (0.2 mmoll-1) and then removed.