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Fig. 3. Effects of angiotensin II (ANG II; 10-8 mol l-1) before and after treatment with CGP42112 (10-6 mol l-1), losartan (10-6 mol l-1) and CV11974 (10-7 mol l-1) on stroke volume (VS) and stroke work (WS) in isolated and perfused paced eel hearts. For details, see Materials and methods. Percentage changes are shown as means ± S.E.M. of 4-5 experiments for each drug. *Significantly different from the control value (P<0.05).