Fig. 3. Thin-section electron microscopic analysis of vesicles associated with comet tails on endosomes. Cell-free reactions were fixed in perfusion chambers and processed for electron microscopy. A gallery of representative images was assembled to highlight the odd shapes, tubular processes, and multivesicular lumens of vesicles associated with tails. Note the clear circular profiles and mitochondria, none of which are associated with comet tails. Bars, 500 nm. Reproduced from Taunton et al. (2000), with permission from the Rockefeller University Press.