Fig. 6. The relationship between the ordered pathway of thick filament assembly, structure and expression. The ordered assembly pathway for C. elegans thick filaments presented by Epstein et al. (1985, 1986) and the structural and synthetic effects of mutants is presented diagrammatically. The relative positions of myosin A and B are indicated on the upper surface, and the position of paramyosin and the filagenins are indicated by exposing the core in the lower half of the filament schematic. The diagram is a modification based on Epstein et al. (1985) and Hoppe and Waterston (2000) that includes the observations on expression presented in the present study.