Fig. 3. Rates of lactate accumulation of cells incubated under iso- (284 mosmol l^–1), hypo- (166 mosmol l^–1) or hyperosmotic conditions (465 mosmol l^–1). Rates were calculated from the difference in lactate concentration at the onset and the end of each period, divided by the duration of the period. Data are means + S.E.M. of 11 experiments.