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Fig. 4. Carbonic anhydrase from the midgut of larval Aedes aegypti. (A) Alignment (BLAST) of the predicted amino acid sequence of Aedes aegypti cDNA (A-CA) (GenBank accession number AF395662) with several known {alpha}-carbonic anhydrases. Regions of exact homology across all species are highlighted in blue (100 %); regions with less homology are highlighted in red (>75 %) and green (>50 %). Similar amino acid residues have been included in the shading. (B) A homology tree comparing A-CA and several vertebrate {alpha}-carbonic anhydrases (DNAman software).