Fig. 1. Dose–response curves for the effect of Tenebrio molitor diuretic peptides Tenmo-DH₃₇ (filled squares) and Tenmo-DH₄₇ (open circles) on fluid secretion rates. Results are expressed as a percentage of the maximal response obtained in the presence of 8-bromo-cyclic AMP (0.1 mmol l^–1). Data points are the mean of 6–12 determinations for Tenmo-DH₃₇ and 6–7 determinations for Tenmo-DH₄₇; vertical lines represent ± 1 S.E.M. The EC₅₀ values are 0.12 nmol l^–1 for Tenmo-DH₃₇ and 26 nmol l^–1 for Tenmo-DH₄₇ (r² values for the curve fits were 0.95 and 0.96, respectively).