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Fig. 7. CRF is expressed within a small set of neuroendocrine cells in the CNS. (a) Immunocytochemical localization of Drome-DH44 in the larval nervous system. There are three cells (arrows) in each cerebral lobe with axons running to the corpus cardiacum (CC). (b) In the adult these six neuroendocrine cells are located in the pars intermedia. (c) In situ hybridization with antisense RNA identifies the same cells in the larval nervous system.