Fig. 3. Drome DH₄₄ increases fluid secretion rates. (A) Typical experiment, showing DromeDH₄₄-stimulated fluid secretion at 10^-7 moll^-1. The peptide was added at 30 min (arrow), and secretion rates measured as described in Materials and methods. Values are mean fluid secretion rates (nl min^-1) ± S.E.M. (N=6-9). Rates of DromeDH₄₄-stimulated secretion at 40-60 min differ significantly from control (asterisks; P<0.05). (B) Dose—response plot for Drome DH₄₄ stimulation of fluid secretion. Stimulated secretion rates were obtained from the typical assays shown in A. To normalise and compare data between different experiments, the results are expressed as the percentage increase of basal rate on peptide stimulation (maximal stimulated rate—mean basal rate)/basal ratex100) ± S.E.M. (N=7-9). Stimulation is significant (P<0.05) at concentrations above 10^-8 moll^-1.