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Fig. 2. Force generation measured with a strain gauge in response to depolarisation produced by an elevation of external K+ concentration to 100 mmol l-1 in red skeletal muscle fibres. The red muscle fibre tissue was pre-soaked in 0Ca2+-ASW containing 10 mmol l-1 Co2+ for 1.5 h. 0.6 mol l-1 KCl solution was added to the bath at the time indicated (+KCl), and the external solution was switched back to the original 0Ca2+-ASW containing 10 mmol l-1 Co2+ at time (-KCl).