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Fig. 1. (A) Tension recording showing the effect of sodium nitroprusside (SNP) on the lateral aorta. The aorta was exposed to endothelin-1 (ET-1; 10-8 mol l-1) until a maximal constriction was achieved and then SNP (10-4 mol l-1) was added. SNP caused a marked vasodilation. (B) Mean responses (% vasodilation) of pre-constricted lateral and dorsal aortae to SNP (10-4 mol l-1; N=5).