Fig. 10. Lack of GPI anchor motif in ISL1194_5nuc: alignments of I. scapularis 5'-nucleotidase with rat, mouse (Mus), human (Homo), bovine (bos), and Boophilus tick 5'-nucleotidase. Identical residues in five or more sequences are bold with gray background. Similar polar or hydrophobic amino acids are shown with gray background. The arrow indicates the conserved serine residue involved in the GPI anchor of 5'-nucleotidases. The box shows the hydrophobic carboxyterminal region, which penetrates the cell membrane. Green background in the box indicates hydrophobic amino acid residues.