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Fig. 4. Time course of the inward negative uncorrected short-circuit current (Itot) measured over the split gill half-lamella of Carcinus maenas during application (bars) of basolateral colchicine (0.2 mmol l-1) and cytochalasin D (5 µmol l-1). The amplitudes of the current deflections, which are due to voltage pulses of 1 mV, are inversely proportional to the resistance between the tips of the voltage electrodes.