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Fig. 5. Influence of exercise on arterial and venous PO2 and O2 content (solid symbols) in relation to the hemoglobin oxygen dissociation for V. mertensi. Values are means ± 1 S.D. (N=6). The open symbols are actual measured values of PaO2 and CaO2 determined at rest. The curve labelled `Exercise' has been adjusted according to pHv and the Bohr effect (see Results). The right panel is a graphical representation of the Fick principle showing the relative contributions of cardiac output (tot) and arterial—venous O2 content difference (CaO2—CO2) to O2 (the shaded area) during rest (cross hatch) and exercise (stippled).