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Fig. 1. Original recording of short-circuit current (Isc) from leech integument adapted to high-salinity water. Increasing concentrations of ATP (in mmol l-1) were added to the basolateral compartment at the indicated times. Note the weak decrease in Isc in response to 10 mmol l-1 ATP. The current sensitive to 100 µmol l-1 amiloride was determined before superfusion with Na+-free Ringer's solution; periods of superfusion are shown below the recording.